MDM2 (Murine Double Minute 2 / MDM2) — FISH
FISH Probes:
MDM2 (12q15) | Chromosome 12 (Centromere 12)
Clinical Indication: Liposarcoma
Method:
Fluorescence in situ hybridization (FISH) to assess MDM2 gene copy number relative to chromosome 12
MDM2
- FISH
Specimen Requirements
Bone marrow aspirate: N/A
Peripheral blood: N/A
Fluids: N/A
Paraffin block: Send paraffin block. Also send circled H&E slide for tech-only (required).
Cut slides: H&E slide (required) plus 4 unstained slides cut at 4-5 microns. Circle H&E slide for tech-only.
Storage and Transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.
CPT Code(s)*
88377x1 manual or 88374x1 automated.
Turnaround time
3-5 Days
Level of Service
- Global
- Tech Only
Integrations
Request electronic integrations →
New York Approved: Yes
*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
Biomarkers
Fluorescence In Situ Hybridization (FISH)
| Amplification(s) | |||||
|---|---|---|---|---|---|
| MDM2 | |||||
Last Updated: March 31, 2026