The combination of p63 + CK HMW + P504S (PIN-4 cocktail) can be extremely useful for diagnosing prostatic intraepithelial neoplasia (PIN) and/or prostate carcinoma, especially in difficult cases with limited tissue. P504 stains (cytoplasm red) prostate adenocarcinoma and atypical adenomatous hyperplasia. p63 (nuclear brown) and cytokeratin high molecular weight (HMW, cytoplasmic brown) stain basal cells of all normal (negative markers) and benign prostate glands.
Prostate Triple Stain
- Immunohistochemistry (IHC)
Specimen Requirements
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody ordered.
Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Storage and Transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.
CPT Code(s)*
88344 x 1
Turnaround time
24 Hours
Level of Service
- Tech Only
Integrations
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New York Approved: Yes
*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
Biomarkers
Immunohistochemistry (IHC)
| Special Stain | |||||
|---|---|---|---|---|---|
| PAX2 | |||||
Last Updated: January 28, 2026